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--- jnl:gan1995 [2021/05/08 04:20]
admin created
+++ jnl:gan1995 [2021/05/22 04:48] (current)
admin [Commentary]
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 ====Commentary====
+Direct vs direct application
+US wave?
+  - Direct US in chicken -- closest to human
+  - FDP tendon repair in 3rd toe (zone 2)
+  - 4/0 Kessler-Tajima
+  - Post-op immobilization until 4 weeks --> 1/2 kept immobilized, 1/2 allowed to mobilize
+    - mobilized samples discarded because weaker, "unrestricted mobilization at 4 weeks is too early".**// This is not what we do.//**
+  - Treatments: No, early (d7), late US (d42)
+    - 3 min with duty cycle 25%, 10 treatments a day. **//This is not practical//**
+  - sacrificed at 4 and 8 weeks
+  - in-situ ROM 65g on FDP tendon
+  - tensile strength - strain 0.001 strain units - youngs modulus
+  - Histology - 2 each group with blinded assessment:
+> a marked decrease in inflammatory infiltrate and a more regular pattern of scar formation (Fig 5) in the US groups. These effects were more pronounced in the early US group than in the late US group.
+Table 1 - Numerical values of ROM testing
+^ Time ^ No US ^ Early US ^ Late US ^ Unoperated ^
+| 4 wks | 1.9±0.4 (n=9) | 2.9±0.3 (n=10) | - | 7.9±0.3 (n=10)|
+| 8 wks | 2.4±0.4* (n=8) | 4.0±0.5* (n=10) | 3.3±0.4 n=10) | 7.7±0.2 (n=10)|
+ROM =range of movement.
+US - ultrasound.
+Values represent mean_+ SEM (mm).
+* Denotes P < 0.05.
+====See also=====
+  - [[md:flexor_tendon]]
 ====Source=====

Alphonsus Chong's Personal Wiki